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Superparamagnetic nanoparticles for local hyperthermia have taken the interest of researchers as it is one of the safest ways nowadays for local tumor treatment using the heat possibility of the magnetic nanoparticles in the presence of an AC magnetic field. Iron oxide nanoparticles have been considered for magnetic hyperthermia application for a long time ago and have been widely studied. However, further improvement in the magnetic properties is still required to enhance the self-heating generation. Manganese spinel ferrite is considered an alternative material for local magnetic hyperthermia thanks to its biocompatibility and promising magnetic properties.
In this work, superparamagnetic manganese spinel ferrite nanoparticles have been synthesized via the solvothermal process. Solvent effects have been considered by using Ethanol and Ethylene glycol as solvents. XRD patterns showed the crystallization of the prepared samples in the cubic spinel structure with space group Fd3m. TEM images proved the formation of monodispersed nanoparticles. To investigate the magnetic properties, magnetic hysteresis loops along with FMR measurements were performed. Moreover, the self-heating generation over time was measured to evaluate the Specific absorption rate (SAR) of the nanoparticles
