Speaker
Description
One effective antitumoral nano therapy is magnetic hyperthermia, which is mediated by magnetic nanoparticles, primarily for its capacity to eradicate malignancies. The present magnetic hyperthermia with nanoparticles is an experimentally explored method for eliminating cancer cells. Spinel ferrites' regulated particle size and superparamagnetic properties are essential for magnetic hyperthermia applications in the treatment of cancer.
This led to the preparation of $Mg_{1-x}Ca_xFe_2O_4$ (x = 0.1, 0.3, and 0.5) nanoparticles to investigate the structural, magnetic, and magnetic hyperthermia properties. When subjected to an alternating magnetic field, the spinel ferrite single-domain particles generate heat. Here, specific loss power values for $Ca^{2+}$ -doped $MgFe_2O_4$ nanoparticles with particle sizes between 13 and 12 nm are described. One of the greatest values for $Ca^{2+}$ doped $MgFe_2O_4$ nanoparticles to date has been reported for the $Mg_{0.9}Ca_{0.1}Fe_2O_4$ nanoparticles with an average particle size of 13 nm, which had a considerable specific loss power value up to 556.73 W/g at 1 mg/mL
ferrofluid concentration. The induction heating investigation of such nanoparticles confirms
their appropriateness for magnetic hyperthermia treatment of cancer. Optimized nanoparticles
were examined for cytotoxicity against human breast cancer (MDA-MB-23) and prostate
cancer (PC-3) cells in terms of cell viability.
